R-068. Initial results from the comparison of recombinant FSH and urinary FSH in an IVF programme

Cost-effectiveness modelling of recombinant FSH versus urinary FSH in assisted reproduction techniques in the UK.

BACKGROUND The purpose of this study was to undertake an economic evaluation to compare the cost-effectiveness of recombinant (r)FSH with urinary (u)FSH for attaining clinical pregnancy with assisted reproduction. METHODS Mathematical modelling was utilized incorporating a Markovian decision framework and a Monte Carlo simulation. Statistical representations of recurrent events over time were...

Bye-bye urinary gonadotrophins? Recombinant FSH: a real progress in ovulation induction and IVF?

Whether recombinant gonadotrophin products do, indeed, represent progress for routine ovulation induction and IVF cycles, in comparison with urinary products, has remained controversial. Here we review published data with regard to respective risks, outcomes and cost for both medication options. Safety considerations favour recombinant products, while overall outcome and cost considerations fav...

Meta-analysis of recombinant versus urinary-derived FSH: an update.

BACKGROUND The study aim was to analyse the results of randomized controlled trials (RCTs) comparing recombinant FSH and urinary-derived FSH gonadotrophins [hMG, urinary purified FSH (FSH-P) and highly purified FSH (FSH-HP)] in an IVF/ICSI programme. METHODS All published truly RCTs using a long protocol of GnRH agonists for down-regulation, were reviewed. Data of pregnancy rate per started c...

Meta-analysis of recombinant FSH and urinary-derived gonadotrophins for IVF or ICSI.

Di Simone, N., Ferrazzani, S., Castellani, R., De Carolis, S., Manscuso, S. and Caruso, A. (1997) Heparin and low dose aspirin restore placental human chorionic gonadotrophin secretion abolished by antiphospholipid antibodycontaining sera. Hum. Reprod., 12, 2061±2065. Di Simone, N., Meroni, P.L., del Papa, N., Raschi, E., Caliandro, D., De Carolis, C.S., Khamashta, M.A., Atsumi, T., Hughes, G.R...

Efficacy of Highly Purified Urinary FSH versus Recombinant FSH in Chinese Women over 37 Years Undergoing Assisted Reproductive Techniques